UniProtKB/Swiss-Prot PTM Description

Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids (By similarity). Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles

The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains

Glycosylation Sites

Position Structures Description Evidence
SER-53, ASN-59, ASN-191, ASN-289, THR-388 Associated Structures: 2 global GlycoSuite
Site-Specific Information

A number of glycan structures have been assigned to specific glycosylation sites

Position Structures Description Evidence
SER-53 Associated Structures: 2 Site specific GlycoSuite

Glycan Structures

Notes

Accompanying information

  1. SER-53 [NISHIMURA ET AL. (1989) J. BIOL. CHEM. 264:20320-20325
  2. ASN-59, ASN-191, ASN-289 & THR-388 [HOJRUP ET AL. (1985) FEBS LETT. 184:333-338

Structure Format

CFG/Essentials Text Oxford

Sequence

AGSYLLEELFEGHLEKECWEEICVYEEAREVFEDDETTDEFWRTYMGGSPCASQPCLNNGSCQDSIRGYACTCAPGYEGPNCAFAESECHPLRLDGCQHFCYPGPESYTCSCARGHKLGQDRRSCLPHDRCACGTLGPECCQRPQGSQQNLLPFPWQVKLTNSEGKDFCGGVLIQDNFVLTTATCSLLYANISVKTRSHFRLHVRGVHVHTRFEADTGHNDVALLDLARPVRCPDAGRPVCTADADFADSVLLPQPGVLGGWTLRGREMVPLRLRVTHVEPAECGRALNATVTTRTSCERGAAAGAARWVAGGAVVREHRGAWFLTGLLGAAPPEGPGPLLLIKVPRYALWLRQVTQQPSRASPRGDRGQGRDGEPVPGDRGGRWAPTALPPGPLV