Associated Structures
Accession: P01579 UniProtKB/Swiss-Prot Entry
UniProtKB/Swiss-Prot PTM Description
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons
Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161
Notes
Accompanying information
Sequence
MKYTSYILAFQLCIVLGSLGCYCQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ
Biological Associations
Taxonomies
- HOMO SAPIENS > UROGENITAL SYSTEM
Protein
- INTERFERON GAMMA
Source
- ADNEXA UTERI > OVARY > >
- HOMO SAPIENS > UROGENITAL SYSTEM
Taxonomies
- INTERFERON GAMMA
Protein
- ADNEXA UTERI > OVARY > >
Source
References 2
-
The widespread effect of beta 1,4-galactosyltransferase on N-glycan processing
PubMed: 11469797 Year: 2001
-
Remodeling of sugar chain structures of human interferon-gamma.
PubMed: 10764830 Year: 2000