UniCorn - Theoretical N-link Glycan Library
UniCorn is a theoretical N-glycan structure database built from a library of 50 human glycosyltransferases. Enzyme specificities were sourced from major databases including Kyoto Encyclopedia of Genes and Genomes (KEGG) Glycan, Consortium for Functional Glycomics (CFG), Carbohydrate-Active enZymes (CAZy), GlycoGene DataBase (GGDB) and BRENDA. Based on the known activities, a parameter-free model of glycosylation is used to generate a library of theoretically possible N-glycans. UniCorn also aims to provide an effective curation and quality-checking tool of newly discovered curated glycan structures populating UniCarbKB.
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